Wade Wilson was an international assassin who had worked for various governments when he developed an aggressive cancer. In an effort to find a cure, he enrolled in the Weapon X program in Canada, which gave him a healing factor from another member and set him to work for them. When he killed a team member, he was thrown out of the program and was sent to have his abilities removed, where he was experimented on instead. The results of his stay there were a diminished mental state, a healing factor that could not cure his cancer or heal his scars, an infatuation with death, and his freedom to return to for-hire mercenary work. As “The Merc with a Mouth” he set out as Deadpool to kill and have a good time doing it.
Deadpool was created by Fabian Nicieza and Rob Liefeld, first appearing in New Mutants #98 (1991).